Acetyl-L-carnitine is a compound derived from the amino acid L-carnitine, which plays an essential role in energy metabolism. It is naturally produced in the human body and is also found in certain foods. LA carnitine, also called L-carnitine or levocarnitine, is an amino acid necessary for the production of energy from certain fatty acids.

Although L-carnitine and acetyl-L-carnitine have some similarities in their fatty acid transport function, they differ in their structure and biological functions.

Acetyl-L-carnitine is primarily studied for its potential effects on cognition and neuroprotection, while L-carnitine is used more widely for its benefits on fat metabolism and exercise performance.

In the form of acetyl-L-carnitine, and only in this form, it is able to cross the blood-brain barrier and enter the brain. Thanks to this property, it has a beneficial effect on cognition and performs neuroprotective functions. Acetyl-L-carnitine is considered a nootropic, that is, an ingredient that improves mental and cognitive abilities.

Acetyl-L-carnitine has antioxidant properties, which means it can help neutralize free radicals and reduce oxidative stress, which is involved in the aging process and neurodegeneration. It can also protect nerve cells from damage and promote their survival. It can affect neurotransmission in the brain by increasing levels of neurotransmitters such as acetylcholine.

Acetyl-L-carnitine shows promising potential for improving memory, learning, and cognition, especially in people with mild cognitive impairment or neurodegenerative diseases.

Acetyl-L-carnitine acts as a carrier of long chain fatty acids across the mitochondrial membrane. In the mitochondria, acetyl-L-carnitine is converted into acetyl-CoA, a key molecule in energy metabolism. Acetyl-CoA then participates in the Krebs cycle where it is used to produce energy in the form of ATP. By improving the transport of fatty acids and the production of acetyl-CoA, acetyl-L-carnitine helps to optimize energy metabolism.

Acetyl-L-Carnitine 500mg (Ref. 001.1), pot of 90 capsules, €39.

Ingredients per capsule: Acetyl-L-Carnitine, 500mg

Recommended dose: 3 capsules per day.

Common side effects are usually mild and rare. They can include gastrointestinal problems. This supplement is not recommended for pregnant women, breastfeeding women and people with epilepsy. It is always best to consult a doctor for personal recommendations.

Possible combinations:

• CoEnzymeQ10 100mg (Ref. 024.2): Coenzyme Q10 is a powerful antioxidant that plays an important role in energy production in the mitochondria.
• R-Lipoic Acid Sodium Salt 300mg (Ref. 098): Alpha Lipoic Acid is a natural antioxidant that promotes the regeneration of other antioxidants, such as Vitamin C and Vitamin E. The combination of acetyl-L-carnitine with alpha-lipoic acid may enhance its antioxidant and neuroprotective effects.

• TMG (ref. 105.2): TMG can act synergistically with acetyl-L-carnitine by promoting the conversion of homocysteine into methionine, an essential amino acid involved in the production of carnitine. This could potentially increase carnitine levels available for fatty acid transport and optimize cellular energy.